Concept Map

Ontology File

Ontologies Reused

Ontology Prefixes

Conceptual Model

Current Version:

Figure 1 in the model above serves as the overview diagram, showcasing the top level concepts represented by the ontology. The central concepts are Patients, the Symptoms they suffer from, the Conditions they are diagnosed with, and the Treatments that address those conditions. Also included in the overview are the patient’s Genome, and the Genes that are associated with conditions.

Figure 2 goes into further detail about patients and conditions, showcasing subclasses of Condition and Symptom, and data properties of the classes which appeared in Figure 1.

Figures 3a and 3b go into further detail with Treatments, with Figure 3a showcasing the subclasses of Treatment, and 3b focusing on other classes that connect to Treatment, such as Medicinal Product and other terms from the IDMP.

Figure 4 centers on the terms used to capture genetic information, namely Genome, Gene, and Disease-Associated Gene.

Week 12 Version: Week 12 Concept Model

Week 11 Version: Week 11 Concept Model

Week 10 Version: Week 10 Concept Model

Week 8 Version: Week 8 Concept Model

Week 6 Versions: Patient / Illness Model Treatment Model Genetics Model

Ontologies

Personalized Depression Treatment Ontology

Week 12 Ontology: Link

Week 12, with Individuals: Link

Week 11 Ontology: Link

Week 11, with Individuals: Link

Week 10 Ontology: Link

Week 10, with Individuals: Link

Week 9 Ontology: Link

Week 8 Ontology: Link

Week 8, with Individuals: Link

Week 7 Ontology: Link

Week 6 Ontology: Link

Primary Classes and Definitions

1. Patient
   • Definition: role of a person receiving or registered to receive medical treatment
   • Immediate Superclass: party role
   • Example: John Doe, a 45-year-old man admitted to the hospital for suicidal ideations.
   • Reused From: None
2. Treatment
   • Definition: something used to manage, alleviate, or cure a medical condition or disease
   • Immediate Superclass: functional role
   • Example: Cognitive Behavioral Therapy
   • Reused From: None
3. Condition
   • Definition: state of being, such as a state of health
   • Immediate Superclass: situation
   • Example: Major Depressive Disorder
   • Reused From: Identification of Medicinal Products (IDMP)
4. Diagnosis
   • Definition: disorder with which a patient has been identified as having
   • Immediate Superclass: specification
   • Example: persistent depressive disorder
   • Reused From: None
5. Medicinal Product
   • Definition: specification for a pharmaceutical product or combination of pharmaceutical products that may be administered to human beings (or animals) for treating or preventing disease, with the aim/purpose of making a medical diagnosis or to restore, correct or modify physiological functions
   • Immediate Superclass: specification
   • Example: Fluoxetine
   • Reused From: Identification of Medicinal Products (IDMP)
6. Gene
   • Definition: distinct sequence of nucleotides forming part of a chromosome, the order of which determines the order of monomers in a polypeptide or nucleic acid molecule which a cell (or virus) may synthesize
   • Immediate Superclass: constituent
   • Example: SLC6A4
   • Reused From: None
7. Symptom
   • Definition: physical or mental feature which is regarded as indicating a condition of disease
   • Immediate Superclass: aspect
   • Example: anhedonia
   • Reused From: None
8. Undesirable Effect
   • Definition: specification of any potential undesirable side effect, adverse reaction or event, complication, or other similar potential consequence associated with the medicinal product as authorized or under investigation
   • Immediate Superclass: specification
   • Example: Nausea
   • Reused From: Identification of Medicinal Products (IDMP)

Ontologies Reused

IDMP - Identification of Medicinal Products Ontology Link

QV - Commons “Quantity and Units” Link

Ontology Prefixes

Prefix	Links
rdf	Resource Description Framework
rdfs	RDF Schema
owl	Web Ontology Language
xsd	XML Schema Definition
dct	Dublin Core Term
skos	Simple Knowledge Organization System
idmp	Identification of Medicinal Products
qv	Commons Quantities and Units